Priority 1: Does the timing and intensity of therapies (e.g. physical, occupational and speech and language therapy, ‘early intervention’, providing information etc.) alter the effectiveness of therapies for infants and young children with neurodisability, including those without specific diagnosis? What is the appropriate age of onset / strategies / dosage / direction of therapy interventions?
- Stretching programme for ambulant children with cerebral palsy - NIHR Health Technology Assessment Programme commissioning brief advertised to researchers
- Strengthening programme for ambulant adolescents with cerebral palsy - NIHR Health Technology Assessment Programme commissioning brief advertised to researchers
- Intensive interaction for children and young people with profound and multiple learning disabilities - NIHR Health Technology Assessment Programme commissioning brief advertised to researchers
- Therapy interventions for children with neurodisability: a scoping study of current practice and perceived research needs - NIHR scoping study published
Priority 2: To improve communication for children and young people with neurodisability: (a) what is the best way to select the most appropriate communication strategies? And (b) how to encourage staff/carers to use these strategies to enable communication?
- Identifying appropriate symbol communication aids for children who are non-speaking: enhancing clinical decision making - NIHR research published
Priority 4: Does appropriate provision of wheelchairs to enable independent mobility for very young children improve their self-efficacy?
- Cost-effectiveness of earlier provision of powered wheelchair interventions for children with mobility limitations: evidence synthesis and economic model - NIHR research published
Priority 7: Does a structured training programme, medicines and/or surgery speed up the achievement of continence (either/or faecal or urinary) for children and young people with neurodisability?
- Improving continence in children and young people with neurodisability (ICoN): survey of current NHS practice and systematic review of effectiveness, cost-effectiveness and contextual factors that modify implementation of interventions - NIHR research complete
Priority 10: What is the long term safety, effectiveness and sustainability of behavioural strategies and/or drugs (e.g. melatonin) to manage sleep disturbance in children and young people with neurodisability (outcomes include time to onset, duration, and reducing impact on family)?
- Pharmacological and non-pharmacological interventions for non-respiratory sleep disturbances in children with neurodevelopmental disorders: a systematic review - NIHR research published
Priority 13: Are sensory processing/integration therapeutic programmes effective in improving behaviour and/or increasing play/participation for children and young people with neurodisability?
- A pragmatic Randomised Controlled Trial of Sensory Integration Therapy versus usual care for sensory processing difficulties in Autism Spectrum Disorder in children: impact on behavioural difficulties, adaptive skills and socialisation (SenITA) - NIHR research in progress
Priority 14: Are behavioural and sensory interventions (e.g. early intensive behavioural intervention, EarlyBird, encouraging socialisation with peers etc.) effective in managing symptoms of Autistic Spectrum Disorder?
- Intensive behavioural interventions for young children with autism: A systematic review and cost-effectiveness analysis - NIHR research published
- Clinical and cost effectiveness of a parent mediated intervention to reduce challenging behaviour in pre-schoolers with moderate to severe learning disability: a randomised controlled trial - NIHR research in progress
Priority 20: Are oro-motor treatment strategies (e.g. oral motor exercises, sensory stimulation, sensorimotor activities etc.) effective to improve eating and drinking or speech for children and young people with neurodisability? Are there identifiable subgroups that benefit more from the strategies?
- What interventions, which could be delivered at home by parents, are available to improve eating in young people with neurodisability and are suitable for investigation in pragmatic trials? - NIHR research published